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May 1, 2026HLA

Genomic Confirmation of HLA‐C*12:68 by Next Generation Sequencing

Jarret Merschman Justin Kreuter Brittany Schneider Manish J. Gandhi

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Key Points

The aim is to confirm the presence of the HLA-C*12:68 variant using advanced sequencing technology.
Next generation sequencing was employed for genomic analysis.
Focus was on identifying nucleotide substitutions in HLA genes.
Characterization involved examining codon 62 in exon 2.
HLA-C*12:68 was confirmed with a specific nucleotide substitution identified at codon 62.
The study efficiently utilized next generation sequencing to detect the genetic variant.

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Implication

Genomic analysis confirms HLA-C*12:68 variant through next generation sequencing, indicating its importance in genetic research.

Abstract

HLA-C*12:68 is characterised by a single nucleotide substitution in codon 62 in exon 2.

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Cite This Study

Merschman et al. (2026) studied this question.

synapsesocial.com/papers/69fd8021bfa21ec5bbf08923 https://doi.org/10.1111/tan.70740

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