Why the study?
Do longitudinal changes in adiposity affect cardiac remodeling in middle-aged individuals?
Do longitudinal changes in adiposity affect cardiac remodeling in middle-aged individuals?
Increasing adiposity in middle age is associated with concentric left ventricular remodeling, highlighting the importance of weight management to prevent eventual heart failure.
Answers are grounded in this paper and cite their sources.
Does not support practice change; leaves open whether longitudinal adiposity changes drive remodeling.
BACKGROUND: Obesity may increase heart failure risk through cardiac remodeling. Cross-sectional associations between adiposity and cardiac structure and function have been elucidated, but the impact of longitudinal changes in adiposity on cardiac remodeling is less well understood. METHODS AND Similar results were seen with other adiposity indices. CONCLUSIONS: Concentric left ventricular remodeling is the predominant phenotype linked to increasing adiposity in middle age. Our findings support the importance of weight management to prevent secular changes in adiposity, concentric remodeling, and eventual heart failure over time.
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Wilner et al. (2017) studied this question.
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