Why the study?
Do obesity and insulin resistance alter myocardial fatty acid metabolism and efficiency in young women?
Population
31 young women (BMI 19 to 52 kg/m2), including 19 who were obese (BMI >30 kg/m2)
Design
Cross-sectional
Authors
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Supports hypothesis that obesity and insulin resistance affect myocardial metabolism in young women; leaves open need for interventional trials.
Do obesity and insulin resistance alter myocardial fatty acid metabolism and efficiency in young women?
In young women, obesity independently predicts increased myocardial oxygen consumption and decreased efficiency, while insulin resistance predicts increased myocardial fatty acid metabolism.
Peterson et al. (2004) studied this question.
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