Why the study?
What is the frequency of primary hyperaldosteronism in normokalaemic subjects previously diagnosed with essential hypertension when screened with plasma aldosterone to renin ratios?
Population
74 normokalaemic hypertensive subjects previously diagnosed with essential hypertension, and 147 control…
Design
Cross-sectional
Authors
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May warrant targeted screening in severe hypertension; leaves open prospective validation of aldosterone-renin ratio utility.
What is the frequency of primary hyperaldosteronism in normokalaemic subjects previously diagnosed with essential hypertension when screened with plasma aldosterone to renin ratios?
Screening with plasma aldosterone/renin ratio reveals that primary hyperaldosteronism is present in about 2.7% of normokalaemic patients previously diagnosed with essential hypertension.
Brown et al. (1996) studied this question.
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