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To define FFR value ranges associated with inducible ischemia and investigate FFR in normal coronary arteries.

December 1, 1995Circulation

Fractional Flow Reserve

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To define FFR value ranges associated with inducible ischemia and investigate FFR in normal coronary arteries.
Measured FFR in 60 patients undergoing PTCA using Pa, Pd, and Pv during adenosine-induced hyperemia.
Patients had a positive exercise test within 24 hours before PTCA.
FFRmyo values were classified based on their association with inducible ischemia after a follow-up exercise test.
FFRmyo increased from 0.53 before PTCA to 0.88 after PTCA.
FFRmyo values ≤ 0.74 were reliably associated with inducible ischemia.
FFRmyo in normal coronary arteries was 0.98, indicating healthy function.

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Randomized trial evaluates fractional flow reserve for assessing ischemia in coronary arteries, suggesting clinical utility.

Pijls et al. (1995) studied this question.

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