Key result
High-intensity plaque on CMR correlates with higher PCATA and larger low-attenuation plaque volume.
Why the study?
To evaluate the association between high-intensity plaque on CMR imaging and pericoronary adipose tissue attenuation and plaque burden on CCTA in patients with chronic coronary syndrome.
Is high-intensity plaque on CMR associated with increased pericoronary adipose tissue attenuation and vulnerable plaque morphology on CCTA in patients with chronic coronary syndrome?
Observational (n=86)
Blinded image analysis
No
Is high-intensity plaque on CMR associated with increased pericoronary adipose tissue attenuation and vulnerable plaque morphology on CCTA in patients with chronic coronary syndrome?
High-intensity plaque on non-contrast CMR is associated with higher pericoronary adipose tissue attenuation and larger low-attenuation plaque volume, suggesting it reflects both local coronary inflammation and structural plaque vulnerability.
May aid noninvasive detection of high-risk plaques in CCS; leaves open added value for risk prediction pending prospective validation.[[1]](https://www.sciencedirect.
Background: This study aimed to investigate the association between high-intensity plaque (HIP) on cardiac magnetic resonance (CMR) imaging and pericoronary adipose tissue attenuation (PCATA) and plaque burden on coronary computed tomography angiography (CCTA) in patients with chronic coronary syndrome (CCS). Methods:We retrospectively analyzed 104 coronary lesions in 86 patients with CCS who underwent CMR imaging and CCTA before elective percutaneous coronary intervention.HIP was defined as a plaque-to-myocardium signal intensity ratio (PMR) of 1.4 on T1-weighted CMR imaging.The PCATA of the target lesion was assessed, and the mean value was used for the analysis.The plaque morphology and volume of the target lesion were assessed on CCTA based on attenuation values and stratified into calcified, fibrous, fibrous-fatty, and low-attenuation plaques (LAPs).
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Ishii et al. (2026) conducted an observational in Chronic coronary syndrome (n=86). High-intensity plaque (HIP) on CMR vs. Non-HIP on CMR was evaluated on Pericoronary adipose tissue attenuation (PCATA) (p=0.022). High-intensity plaque on cardiac magnetic resonance imaging was significantly associated with higher pericoronary adipose tissue attenuation (-69.3 HU vs -73.9 HU) and larger low-attenuation plaque volume.
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