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May 1, 2025Acta Radiologica OpenOpen Access

Pericoronary fat attenuation in stenotic and vulnerable coronary artery plaques: Implications for coronary artery disease and associated conditions

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Why the study?

Pericoronary adipose tissue density quantifies coronary inflammation and atherosclerosis, but its correlation with plaque features and stenosis degrees in arteries with stenotic vulnerable plaques needed investigation.

Population

103 patients (64M, 39F) who underwent coronary computed tomography

Comparison

PCAT compared across plaque features, stenosis degrees, and coronary artery types

Design

Single-center retrospective study

Authors

BGBurak GünayEducation Training And ResearchMTMuzaffer Savaş TepeEducation Training And ResearchAKAtakan KüskünUsak University

Discussion

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Implication

PCAT may aid noninvasive stenosis assessment on CT; leaves open its role as a biomarker pending prospective validation.

Structured PICO

P
Population
103 patients (64 male, 39 female) who underwent coronary computed tomography
I
Intervention
Measurement of pericoronary adipose tissue density (PCAT) and high-risk plaque features via coronary computed tomography
O
Outcome
Correlation between PCAT and plaque features, as well as stenosis degrees in coronary arteries (LAD, RCA, Cx)surrogate

Pericoronary adipose tissue density (PCAT) correlates significantly with coronary stenosis severity and high-risk plaque features, suggesting its utility as an imaging biomarker for vulnerable plaques.

Cite This Study

Günay et al. (2025) studied this question.

synapsesocial.com/papers/6a83605ac119deb01dc60ec7https://doi.org/10.1177/20584601251342312
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Also Consider

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