Why the study?
Are plasma NT proBNP and CT-1 elevated in patients with aortic stenosis and do they correlate with trans-valvular pressure gradient?
Population
25 subjects, comprising 15 patients with aortic stenosis and 10 controls.
Comparison
Measurement of plasma N-terminal proBNP and… vs Controls
Design
Case-control
Authors
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May support biomarker investigation in AS; hypothesis-generating and should not yet change practice.
Are plasma NT proBNP and CT-1 elevated in patients with aortic stenosis and do they correlate with trans-valvular pressure gradient?
Plasma NT proBNP and CT-1 are elevated in patients with aortic stenosis and correlate with the trans-valvular pressure gradient, suggesting potential utility for non-invasive disease monitoring.
Talwar et al. (2001) studied this question.
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