Key result
Takotsubo syndrome presents as stress-triggered acute transient LV apical ballooning predominantly in postmenopausal women.
Takotsubo syndrome presents similarly to acute coronary syndrome and requires imaging such as ventriculography or echocardiography to identify the characteristic apical ballooning for definitive diagnosis.
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Imaging essential to differentiate from ACS; leaves open generalizability beyond isolated cases.
BACKGROUND: Takotsubo syndrome, also known as stress cardiomyopathy, is a condition triggered by emotional factors or intense physical stress; postmenopausal women are the predominant population. CLINICAL CASES: A series of cases is presented. In the first clinical case a primary takotsubo syndrome is exposed in a 60-year-old female patient with chest pain, ac-companied by exaggerated neurovegetative response related to a previous emotional event. On the second case, a 69-year-old female patient suffered a fall in her own sup-port plane, with direct contusion on the thorax, developing later a secondary takotsubo syndrome. In both cases an electrocardiogram with T-wave reversal and ST segment elevation, cardiac enzyme elevation, and a characteristic imaging study, showing no coronary artery injury, as well as a left ventricle with severe apical hypokinesia giving a characteristic image in the form of a vase of takotsubo. CONCLUSIONS: The diagnosis of takotsubo syndrome is challenging due to the simila- rity of the clinical picture to an acute coronary syndrome. Definitive diagnosis requires a ventriculography that shows the characteristic pattern in the shape of the vessel that gives to the syndrome its name.
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Rolón et al. (2025) conducted a review in Takotsubo Syndrome. Takotsubo syndrome is an acute, transient cardiac condition predominantly affecting postmenopausal women, characterized by left ventricular apical ballooning and often triggered by stress.
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