Key result
Mean platelet volume was not associated with the prevalence of coronary artery disease (OR 0.85; 95% CI 0.7-1.03; P=0.11) or platelet reactivity among diabetic patients.
Why the study?
Is mean platelet volume associated with platelet reactivity and the extent of coronary artery disease in diabetic patients?
Population
1016 consecutive diabetic patients undergoing coronary angiography at a single center in Italy, including a…
Comparison
Mean platelet volume assessment vs Comparison across MPV tertiles
Design
Cohort
Authors
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MPV should not inform CAD risk assessment in diabetes; leaves open utility in other populations or assays.
Cohort (n=1,016)
No
Is mean platelet volume associated with platelet reactivity and the extent of coronary artery disease in diabetic patients?
Effect estimate: OR 0.85 (95% CI 0.7-1.03)
p-value: p=0.11
Mean platelet volume is not associated with platelet reactivity or the prevalence and extent of coronary artery disease in diabetic patients, suggesting it may not be a useful risk factor in this population.
Luca et al. (2013) conducted a cohort in Coronary artery disease in diabetic patients (n=1,016). Mean platelet volume (MPV) vs. Tertiles of MPV was evaluated on Prevalence of coronary artery disease (stenosis >50%) (OR 0.85, 95% CI 0.7-1.03, p=0.11). Mean platelet volume was not associated with the prevalence of coronary artery disease (OR 0.85; 95% CI 0.7-1.03; P=0.11) or platelet reactivity among diabetic patients.
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