Key result
FDG-PET/CT identifies distant metastases in Stewart-Treves syndrome, showing potential for early detection of malignant transformation.
Case Report (n=1)
FDG-PET/CT scan may be a clinically useful imaging modality to detect early malignant transformation in patients with chronic lymphedema.
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Case report data suggest FDG-PET/CT utility in Stewart-Treves syndrome; leaves open prospective validation before clinical adoption.
This 17-year-old woman had chronic congenital lymphedema in the left lower extremity since childhood. She underwent surgeries to remove excessive lymphedematous tissues more than 15 times previously. Histopathology of the specimen from the recent surgery revealed angiosarcoma; therefore, FDG-PET/CT scan was arranged to determine the extent of tumor spread, and distant metastases were discovered. Stewart-Treves syndrome is angiosarcomas that arise secondary to chronic lymphedema. Because of the high lethality of this condition, the FDG-PET/CT scan may be a clinically useful imaging modality to detect the possible malignant transformation earlier for patients with chronic lymphedema.
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Chen et al. (2014) conducted a case report in Stewart-Treves syndrome (n=1). FDG-PET/CT scan was evaluated on Detection of distant metastases. FDG-PET/CT scan successfully detected distant metastases in a 17-year-old woman with Stewart-Treves syndrome, suggesting its potential utility for early detection of malignant transformation.
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