Why the study?
Is atrial fibrillation associated with increased risk of major adverse cardiac events and mortality in patients with symptomatic peripheral artery disease?
Is atrial fibrillation associated with increased risk of major adverse cardiac events and mortality in patients with symptomatic peripheral artery disease?
Atrial fibrillation serves as a significant prognostic marker for increased mortality and major adverse cardiac events in patients with symptomatic peripheral artery disease.
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AF may inform risk stratification and monitoring in symptomatic PAD; extends prognostic data but high heterogeneity leaves interventional implications open.
BACKGROUND: Atrial fibrillation (AF) is associated with adverse outcomes in terms of survival and morbidity. Peripheral artery disease (PAD) and AF share several common risk factors and often coexist. Whether AF has a prognostic role in patients with PAD has not been extensively studied. HYPOTHESIS: AF is associated with major adverse cardiac events (MACE) and mortality in symptomatic PAD patients. METHODS: statistic. Sensitivity analyses were performed to test the contribution of each study to the overall results. RESULTS: = 74.3%), without detected publication bias (P = 0.08). CONCLUSIONS: AF is associated with increased risk of mortality and MACE in symptomatic PAD.
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Vrsalović et al. (2017) studied this question.
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