Key result
StO2 reperfusion slope strongly correlates with FMD in healthy young men.
Why the study?
Does NIRS-derived StO2 reperfusion rate correlate with ultrasound-derived FMD for assessing vascular endothelial function in healthy young men?
Cross-Sectional (n=20)
Does NIRS-derived StO2 reperfusion rate correlate with ultrasound-derived FMD for assessing vascular endothelial function in healthy young men?
Effect estimate: r = 0.63
p-value: p=0.003
NIRS-derived slope 2 StO2 significantly correlates with FMD, suggesting it can be used as a non-invasive measure of vascular endothelial function.
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Hypothesis-generating for NIRS StO2 reperfusion as endothelial function surrogate in healthy men; requires validation before clinical use.
McLay et al. (2015) conducted a cross-sectional in Healthy (n=20). Near-infrared spectroscopy (NIRS) measurement of StO2 reperfusion slope vs. Ultrasound-derived flow-mediated dilation (FMD) was evaluated on Correlation between the reperfusion rate of StO2 and FMD (r = 0.63, p=0.003). The reperfusion slope of tissue oxygen saturation (StO2) measured by near-infrared spectroscopy significantly correlated with flow-mediated dilation (r = 0.63, P = 0.003) in healthy young men.
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