Why the study?
This study aimed to determine the impact of heart failure on clinical outcomes in patients with atrial fibrillation.
Does the presence of heart failure increase mortality and cardiovascular events in patients with atrial fibrillation?
Population
688 AF patients with available HF data from Polish EORP-AF registry participants
Comparison
Patients with HF vs without HF
Design
Registry-based observational study
Follow-up
one-year
Key result
Heart failure in patients with atrial fibrillation was associated with a significantly higher rate of all-cause death compared to those without heart failure (aHR 5.61; 95% CI 1.94-16.22; P<0.01).
Authors
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HF with AF linked to higher mortality; leaves open optimal interventions across phenotypes in prospective studies.
Observational (n=688)
Yes
Does the presence of heart failure increase mortality and cardiovascular events in patients with atrial fibrillation?
Effect estimate: aHR 5.61 (95% CI 1.94-16.22)
p-value: p=<0.01
In patients with atrial fibrillation, the presence of concomitant heart failure is associated with a more than five-fold increased risk of all-cause mortality at one year, regardless of ejection fraction phenotype.
Budnik et al. (2022) conducted an observational in Atrial fibrillation (n=688). Heart failure vs. No heart failure was evaluated on All-cause death (aHR 5.61, 95% CI 1.94-16.22, p=<0.01). Heart failure in patients with atrial fibrillation was associated with a significantly higher rate of all-cause death compared to those without heart failure (aHR 5.61; 95% CI 1.94-16.22; P<0.01).