Key result
Low-pressure baroreflexes play little or no role in regulating arginine vasopressin release in fluid-restricted humans, whereas high-pressure baroreflexes and arterial pulse pressure are more essential.
Why the study?
Do low- and high-pressure baroreflexes influence arginine vasopressin release in humans?
Population
Overnight fluid-restricted humans
Design
Other
Authors
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Should not yet change AVP-related fluid protocols; hypothesis-generating for baroreflex-targeted physiologic models.
Do low- and high-pressure baroreflexes influence arginine vasopressin release in humans?
In humans, high-pressure baroreflexes driven by changes in arterial pulse pressure are more essential for modulating vasopressin release than low-pressure baroreflexes.
Peter Norsk (1989) studied Healthy humans (implied). Water immersion, lower body positive/negative pressure, negative pressure breathing, and neck suction was evaluated on Arginine vasopressin (AVP) release. Low-pressure baroreflexes play little or no role in regulating arginine vasopressin release in fluid-restricted humans, whereas high-pressure baroreflexes and arterial pulse pressure are more essential.
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