Key result
Antihypertensive drugs decrease central aortic systolic pressure by reducing wave reflection, a beneficial effect that is not detected by standard peripheral blood pressure measurements.
Design
Review
Authors
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Central pressure reduction may inform therapy beyond brachial readings; leaves open whether targeting it improves outcomes.
Key points are not available for this paper at this time.
Michael R. OʼRourke (1990) studied this question. Antihypertensive drugs decrease central aortic systolic pressure by reducing wave reflection, a beneficial effect that is not detected by standard peripheral blood pressure measurements.
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