Key result
Elevated baseline brachial pulse pressure was associated with 4-year progression of common carotid intima-media thickness (partial correlation coefficient=0.11, P<0.001).
Why the study?
Is brachial pulse pressure associated with common carotid intima-media thickness cross-sectionally and longitudinally in a general population?
Population
957 volunteers aged 59 to 71 years recruited from the electoral rolls of the city of Nantes (western France)
Design
Cohort
Follow-up
4 years
Authors
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Brachial pulse pressure may identify older adults at risk for carotid thickening; leaves open whether it is causal or a modifiable target.
Observational (n=957)
No
Is brachial pulse pressure associated with common carotid intima-media thickness cross-sectionally and longitudinally in a general population?
Effect estimate: partial correlation coefficient 0.11
p-value: p=<0.001
Elevated brachial pulse pressure is associated with the progression of carotid intima-media thickness over 4 years, and increased CCA-IMT predicts pulse pressure widening.
Zureik et al. (1999) conducted an observational in General population (n=957). Brachial pulse pressure was evaluated on 4-year longitudinal change in common carotid intima-media thickness (partial correlation coefficient 0.11, p=<0.001). Elevated baseline brachial pulse pressure was associated with 4-year progression of common carotid intima-media thickness (partial correlation coefficient=0.11, P<0.001).
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