Why the study?
Does local debridement and a closed irrigation system with tyloxapol and tobramycin eradicate infection in patients with infected or eroded permanent pacemaker pockets?
Does local debridement and a closed irrigation system with tyloxapol and tobramycin eradicate infection in patients with infected or eroded permanent pacemaker pockets?
Local debridement combined with a closed irrigation system using tyloxapol and tobramycin successfully salvaged infected pacemaker pockets without requiring complete system extraction in a small case series.
May support pocket salvage without extraction in select cases; leaves open need for prospective trials.
Over a period of 71 months, 19 patients were treated for infected or eroded permanent pacemaker pockets. All cases were treated with local debridement and insertion of a closed irrigation system using a solution of tyloxapol and tobramycin. Successful eradicaiton of the infection, without complete replacement of the pacemaker system, was achieved in all cases.
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Hurst et al. (1986) studied this question.
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