Key result
Conservative treatment of pacemaker pocket infections shows 0 re-infections, matching complete system removal.
Why the study?
There is conflicting information regarding the long-term efficacy of conservative treatment for pacemaker pocket site infections.
Does conservative treatment prevent re-infection in patients with pacemaker pocket site infection compared to standard treatment?
Cohort (n=132)
No
Does conservative treatment prevent re-infection in patients with pacemaker pocket site infection compared to standard treatment?
Absolute Event Rate: 0% vs 0%
Conservative treatment of pacemaker pocket site infections appears to be as effective as standard extraction and reimplantation in preventing long-term re-infection.
Conservative management may be feasible in select cases; leaves open need for RCTs before practice change.
Introduction: The increasing frequency of cardiac device use has led to an increase in complication rates.The standard treatment for cardiac device-related infections is removal of the entire pacemaker system and reimplantation from the contralateral side after systemic antibiotherapy.The efficacy of various conservative treatments has been established for many years, but there is conflicting information in the literature regarding long-term efficacy.Aim: Our study investigated the long-term efficacy of conservative treatment in patients with pacemaker pocket site infection. Material and methods:In this retrospective study, according to the exclusion criteria, 132 patients were included.Patients were divided into conservative and standard treatment groups.Conservative treatment was considered to be opening the pacemaker pocket capsule, removing all infected and necrotic tissue, cleaning the capsule, and embedding the battery in the prepectoral region in the subpectoral muscle region.Results: The follow-up time was 36 ±12.96 months in the conservative treatment group and 39.6 ±10.8 months in the standard treatment group.During this period, no re-infection at the pacemaker pocket site was observed in either group.Examination of the swab cultures of the patients' pacemaker wounds revealed negative culture results in 15 patients (15 out of 60) in the conservative treatment group.In the standard treatment group, 60 patients (60 out of 72) were culture-negative.This difference was statistically significant (p = 0.04).Conclusions: After a rigorous evaluation, conservative treatment is considered effective and safe in the long term in patients with device pocket site infection.
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Eryılmaz et al. (2022) conducted a cohort in Pacemaker pocket site infection (n=132). Conservative treatment (limited debridement, irrigation, and subpectoral battery relocation) vs. Standard treatment (removal of entire pacemaker system and contralateral reimplantation) was evaluated on Re-infection at the pacemaker pocket site. Conservative treatment of localized pacemaker pocket site infections resulted in zero re-infections over a mean follow-up of 36 months, demonstrating long-term safety and efficacy comparable to standard complete system removal.
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