Prediction of residual angina after percutaneous coronary intervention
Key result
A hierarchical model predicts residual angina six months post-PCI, affecting ~24% of patients.
- c-index 0.75
- n=2,573
Population
2573 patients who had percutaneous coronary intervention at 10 US hospitals for stable angina, unstable…
Design
Cohort
Follow-up
6 months
Authors
Discussion
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Implication
Residual angina persists in 24% post-PCI; leaves open whether addressing identified predictors improves outcomes in prospective trials.
Study Design
Type
Cohort (n=2,573)
Multicenter
Yes
Structured PICO
P
Population
2573 patients who had percutaneous coronary intervention (PCI) at 10 US hospitals for stable angina, unstable angina, or non-ST-elevation myocardial infarction (NSTEMI)
I
Intervention
Percutaneous coronary intervention (PCI)
O
Outcome
Residual angina 6 months after PCI, assessed with the Seattle Angina Questionnaire angina frequency score (categorized as none vs. any angina; score = 100 vs. <100)patient reported
Main Result
Effect estimate: c-index 0.75
A newly developed predictive model using patient factors such as age, economic status, depression, and baseline antianginal use can accurately predict the likelihood of residual angina 6 months after PCI.
Cite This Study
Arnold et al. (2015) conducted a cohort in Stable angina, unstable angina, or NSTEMI (n=2,573). Percutaneous coronary intervention (PCI) was evaluated on Angina 6 months after PCI (Seattle Angina Questionnaire score <100) (c-index 0.75). A hierarchical logistic regression model predicted residual angina 6 months after PCI with a c-index of 0.75, revealing that 24% of patients continued to experience angina post-procedure.