Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization
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Key result
Persistent or recurrent angina after percutaneous coronary intervention affects 20-40% of patients and is frequently driven by coronary microvascular dysfunction or epicardial vasospasm.
Why the study?
Persistent or recurrent angina affects 20-40% of patients post-PCI with significant economic burden, but practice guideline recommendations are unclear and mechanistic evidence gaps remain.
Design
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Implication
Supports structured evaluation for microvascular causes in post-PCI angina; leaves open therapeutic trials in this population.
Structured PICO
P
Population
Patients with persistent or recurrent angina following percutaneous coronary intervention (PCI)
Persistent or recurrent angina post-PCI affects up to 20-40% of patients, often driven by coronary microvascular dysfunction or epicardial spasm, necessitating a structured diagnostic approach.
Limitations
- Lack of randomized controlled trials for the management of post-PCI angina
- Gaps in evidence regarding the mechanisms of post-PCI angina
Cite This Study
Crea et al. (2018) conducted a review in Persistent or recurrent angina following percutaneous coronary intervention. Diagnostic evaluation of post-PCI angina was evaluated. Persistent or recurrent angina after percutaneous coronary intervention affects 20-40% of patients and is frequently driven by coronary microvascular dysfunction or epicardial vasospasm.
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