Key result
Female gender linked to ~35% higher in-hospital mortality risk after PCI.
Why the study?
Does female gender impact in-hospital mortality in patients undergoing percutaneous coronary intervention?
Population
130,985 PCI procedures in patients in Belgium from January 2006 to February 2011.
Comparison
Female gender vs Male gender
Design
Cohort
Follow-up
in-hospital
Authors
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May inform sex-specific PCI risk models; leaves open whether targeted strategies reduce mortality in women.
Cohort (n=130,985)
Yes
Does female gender impact in-hospital mortality in patients undergoing percutaneous coronary intervention?
Effect estimate: OR 1.35 (95% CI 1.22-1.49)
Absolute Event Rate: 2.5% vs 1.6%
p-value: p=<0.0001
Female sex is an independent predictor of higher in-hospital mortality following PCI, highlighting the need for gender-specific risk assessment.
Lempereur et al. (2016) conducted a cohort in Coronary artery disease (n=130,985). Female gender vs. Male gender was evaluated on All-cause in-hospital mortality (OR 1.35, 95% CI 1.22-1.49, p=<0.0001). Female gender was an independent predictor of in-hospital mortality following percutaneous coronary intervention, associated with a 35% increased risk of death compared to males (adjusted OR 1.35).
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