Key result
No clinical data is present in the provided text, which consists only of journal editorial board information.
Why the study?
Does the choice of coumarin anticoagulant and presence of specific comorbidities increase the risk of overanticoagulation (INR >= 6.0) in outpatients?
Population
17,056 outpatients of an anticoagulation clinic using coumarin anticoagulants. The nested case-control…
Comparison
Acenocoumarol therapy and presence of specific… vs Phenprocoumon therapy and absence of specific…
Design
Case-control
Authors
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Acenocoumarol and comorbidities may raise overanticoagulation risk in outpatients; leaves open tailored monitoring or agent selection.
Does the choice of coumarin anticoagulant and presence of specific comorbidities increase the risk of overanticoagulation (INR >= 6.0) in outpatients?
In outpatients on coumarin anticoagulants, acenocoumarol use and specific acute or chronic comorbidities (such as heart failure, impaired liver function, diarrhea, and fever) significantly increase the risk of severe overanticoagulation.
Beest et al. (2001) studied this question. No clinical data is present in the provided text, which consists only of journal editorial board information.
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