Key result
Strain transfer through the aortic valve matrix is anisotropic and indirect, with local strains under circumferential loading being only one-third of applied values.
Population
Aortic valve leaflets (radial and circumferential samples)
Comparison
Quasi-static mechanical characterization and… vs Radial vs circumferential loading
Design
Preclinical
Authors
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Animal data on aortic valve matrix anisotropy warrant human validation; leaves open implications for tissue engineering or cell protection.
Strain transfer through the aortic valve matrix is anisotropic and indirect, potentially protecting interstitial cells from damage during normal valve function.
Lewinsohn et al. (2011) studied Aortic valve biomechanics. Radial and circumferential loading was evaluated on Strain transfer through the valve matrix. Strain transfer through the aortic valve matrix is anisotropic and indirect, with local strains under circumferential loading being only one-third of applied values.
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