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March 19, 2008European Heart JournalOpen Access

The timing of development and subsequent clinical course of heart failure after a myocardial infarction

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Key result

The development of heart failure preceded death in 83.6% (235 of 281) of patients who died after discharge following an index myocardial infarction.

Why the study?

What is the natural history, incidence, and prognostic impact of heart failure development after a myocardial infarction?

Population

896 patients with a death or discharge diagnosis of myocardial infarction in 1998 from hospitals serving a…

Design

Cohort

Follow-up

Up to December 2005 (approximately 7 years)

Authors

ATAzam TorabiImperial College Healthcare NHS TrustJohn G.F. ClelandJohn G.F. ClelandHeart Failure / CardiomyopathyNKNasir KhanUniversiti Teknologi Petronas

Discussion

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Implication

Suggests prioritizing HF prevention post-MI; leaves open whether targeted strategies improve survival.

Study Design

Type

Cohort (n=896)

Multicenter

Yes

Structured PICO

What is the natural history, incidence, and prognostic impact of heart failure development after a myocardial infarction?

P
Population
896 patients with a death or discharge diagnosis of myocardial infarction in 1998 from hospitals serving a local community of 600,000 people.
O
Outcome
Development of heart failure (defined as signs and symptoms consistent with that diagnosis and treated with loop diuretics) and deathhard clinical

The development of heart failure precedes death in the vast majority of patients who die following a myocardial infarction, highlighting the critical need for HF prevention post-MI.

Cite This Study

Torabi et al. (2008) conducted a cohort in Myocardial infarction (n=896). Natural history of heart failure was evaluated on Development of heart failure and mortality. The development of heart failure preceded death in 83.6% (235 of 281) of patients who died after discharge following an index myocardial infarction.

synapsesocial.com/papers/6a088ec5df3db8739810a1edhttps://doi.org/10.1093/eurheartj/ehn096

Topics

HFrEF treatmentHeart failureHeart failure hospitalization
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