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January 1, 2020The Anatolian Journal of CardiologyOpen Access

Clinical characteristics and in-hospital outcomes of acute decompensated heart failure patients with and without atrial fibrillation

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Key result

Atrial fibrillation shows no link to higher in-hospital mortality in acute decompensated heart failure.

  • P=0.121
  • n=1,606

Why the study?

The impact of atrial fibrillation on in-hospital outcomes in acute decompensated heart failure is controversial.

Does the presence of atrial fibrillation worsen in-hospital outcomes in patients hospitalized with acute decompensated heart failure?

Population

1,606 hospitalized patients with ADHF in Turkey

Comparison

ADHF with AF vs ADHF without AF

Design

Multicenter observational study

Authors

UKUmut Kocabaş

Discussion

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Overview

May not warrant AF-targeted interventions to reduce in-hospital mortality in ADHF; leaves open effects on other endpoints or longer-term outcomes.

Study Design

Type

Observational (n=1,606)

Multicenter

Yes

Structured PICO

Does the presence of atrial fibrillation worsen in-hospital outcomes in patients hospitalized with acute decompensated heart failure?

P
Population
1,606 hospitalized patients with acute decompensated heart failure (ADHF) from the Journey HF-TR study in Turkey
I
Intervention
Presence of atrial fibrillation (history of AF or new-onset AF during hospitalization)
C
Comparator
Absence of atrial fibrillation
O
Outcome
In-hospital outcomes including adverse events, length of stay, and all-cause mortalityhard clinical

Main Result

Absolute Event Rate: 8.9% vs 6.8%

p-value: p=0.121

In patients hospitalized with acute decompensated heart failure, the presence of atrial fibrillation is common but does not significantly increase in-hospital mortality or adverse events.

Cite This Study

Umut Kocabaş (2020) conducted an observational in Acute decompensated heart failure (n=1,606). Atrial fibrillation vs. Without atrial fibrillation was evaluated on In-hospital all-cause mortality (p=0.121). Atrial fibrillation in patients hospitalized with acute decompensated heart failure was not associated with a significant increase in in-hospital all-cause mortality (8.9% vs. 6.8%; p=0.121).

synapsesocial.com/papers/6a08aba67de338f10b10e75ahttps://doi.org/10.14744/anatoljcardiol.2020.94884
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND‐HF) Trial2015 · 35 citations
  2. 2Atrial Fibrillation and Heart Failure — Five More Years2004 · 44 citations
  3. 3Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study2009 · 244 citations
  4. 4Independent Contribution of Diabetes to Increased Prevalence and Incidence of Atrial Fibrillation2009 · 189 citations
  5. 5Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study2006 · 1,966 citations