Key result
Computational AF modelling clarifies the complex interplay between atrial geometry, fibrosis distribution, and electrophysiology.
Why the study?
AF involves complex initiation, maintenance, and progression mechanisms, and computational modelling offers a framework to integrate experimental and clinical findings for mechanistic research.
Computational modelling provides an essential framework for integrating experimental and clinical findings to understand the complex mechanisms of atrial fibrillation.
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Supports computational AF research; leaves open clinical translation pending prospective validation.
Aronis et al. (2019) conducted a review in Atrial Fibrillation. Computational modelling and simulations was evaluated. Computational modelling of atrial fibrillation provides essential mechanistic insights into the complex interplay between atrial geometry, fibrosis distribution, and electrophysiology.
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