Key result
Genome-wide association studies applied to coronary artery disease, myocardial infarction, and heart failure have yielded limited insights into the genetic etiology of these diseases to date.
Population
Cohorts with coronary artery disease, myocardial infarction, and heart failure
Design
Review
Authors
Loading...
Current GWAS limitations in CAD and HF advise against routine genetic testing; leaves open need for alternative discovery methods.
This review summarizes the limited insights gained from GWAS in coronary artery disease and heart failure to date and discusses future directions for identifying important genes.
Dorn et al. (2009) conducted a review in Coronary artery disease, myocardial infarction, and heart failure. Genome-wide association studies was evaluated. Genome-wide association studies applied to coronary artery disease, myocardial infarction, and heart failure have yielded limited insights into the genetic etiology of these diseases to date.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: