Key result
High waist-to-hip ratio is linked to ~100% higher risk of subclinical LV dysfunction without general obesity.
Why the study?
Does abdominal adiposity or general obesity associate with subclinical left ventricular systolic dysfunction in an elderly population?
Population
729 elderly participants from the Cardiovascular Abnormalities and Brain Lesions study, mean age 71 ± 9…
Comparison
Abdominal adiposity and general obesity vs Normal waist-to-hip ratio and normal body mass…
Design
Cohort
Authors
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High WHR may flag subclinical LV dysfunction risk in elderly patients irrespective of BMI; leaves open causal role and intervention effects.
Cohort (n=729)
Does abdominal adiposity or general obesity associate with subclinical left ventricular systolic dysfunction in an elderly population?
Effect estimate: OR 2.0 (95% CI 1.1-3.6)
p-value: p=0.020
Abdominal adiposity, but not general obesity (BMI), is independently associated with subclinical left ventricular systolic dysfunction measured by global longitudinal strain in the elderly.
Russo et al. (2016) conducted a cohort in Subclinical left ventricular systolic dysfunction (n=729). High waist-to-hip ratio (abdominal adiposity) vs. Normal waist-to-hip ratio was evaluated on Subclinical LV dysfunction by global longitudinal strain in participants without general obesity (OR 2.0, 95% CI 1.1-3.6, p=0.020). High waist-to-hip ratio was associated with subclinical left ventricular dysfunction by global longitudinal strain in participants without (OR 2.0; 95% CI 1.1-3.6) and with general obesity (OR 5.4).
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