Impact of mid-life cardiovascular health on cognitive change in a bi-ethnic cohort

Figure 1.. Association of physical activity with cognitive decline in the (a) total cohort, (b) Mexican American cohort, and the (c) non-Hispanic White cohort. This plot shows the slope of MMSE over time predicted by the interaction with physical activity LS7 categories, poor and a combination of intermediate and ideal, with cognitive decline. The poor physical activity LS7 category included individuals who reported 0 minutes of exercise a week. Intermediate/ideal physical activity included individuals who recorded any (>0) exercise minutes a week. Predicted outcomes and confidence interval bands are shown, with red representing the poor physical activity LS7 category and blue the intermediate/ideal category. In the analysis, only the (a) total cohort and (b) Mexican American cohort showed significant differences between the slope of the poor physical activity LS7 category and the intermediate/ideal category.

Figure 2.. Association of blood glucose with cognitive decline in the (a) total cohort, (b) Mexican American cohort, and (c) non-Hispanic White cohort. This plot shows the slope of MMSE over time predicted by the interaction of the two LS7 blood glucose categories, poor and a combination of intermediate and ideal, with cognitive decline. The poor blood glucose LS7 category included individuals with a fasting blood glucose ≥ 126 mg/dL. Intermediate/ideal category included individuals with a fasting blood glucose < 125 mg/dL or < 100 mg/dL if treated. Predicted outcomes and confidence interval bands are shown, with red representing the poor blood glucose LS7 category and blue the intermediate/ideal category. The significant results from our analysis were in the (c) non-Hispanic White cohort.

Figure 3.. Association of BMI with cognitive decline in the (a) total cohort, (b) Mexican American cohort, and (c) non-Hispanic White cohort. This plot shows the slope of MMSE predicted over time by the interaction of BMI LS7 categories, poor and a combination of intermediate and ideal, with cognitive decline. The poor BMI LS7 category consisted of individuals with a BMI ≥30 kg/m2. Intermediate/ideal category included individuals with a BMI < 30 kg/m2.Predicted outcomes and confidence interval bands are shown, with red representing the poor BMI LS7 category and blue the intermediate/ideal category. Significant results from our analysis were in the (a) total cohort and (b) Mexican American cohort.