Key result
BNP was the only factor independently associated with one-year cardiovascular events or death, despite event rates ranging from 2.9% in normal LV function to 60% in systolic dysfunction.
Cohort
BNP is an independent predictor of cardiovascular events and mortality in patients, regardless of underlying left ventricular systolic or diastolic function patterns.
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Supports BNP for prognostication independent of LV function; should not yet change practice pending randomized data.
Davos et al. (2000) conducted a cohort in Chronic Heart Failure. BNP vs. LV function parameters was evaluated on cardiovascular events (heart failure or dead). BNP was the only factor independently associated with one-year cardiovascular events or death, despite event rates ranging from 2.9% in normal LV function to 60% in systolic dysfunction.
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