Effects of individual risk factors on the incidence of cardiovascular events in the treated hypertensive patients of the Hypertension Optimal Treatment Study

18,790 hypertensive patients subjected to pronounced blood pressure lowering

Presence of individual cardiovascular risk factors (male gender, age ≥ 65 years, smoking, high serum cholesterol > 6.8 mmol/l, high serum creatinine > 155 μmol/l, diabetes, and ischaemic heart disease)

Absence of the respective individual cardiovascular risk factors

Incidence of cardiovascular events, cardiovascular mortality, total mortality, myocardial infarction, and strokehard clinical