Key result
Amiodarone induced torsades de pointes and an increase in QT dispersion of >100% in a patient with a history of quinidine-induced torsades de pointes.
Why the study?
Does amiodarone induce TdP in patients with a history of quinidine-induced TdP?
Case Report (n=1)
Does amiodarone induce TdP in patients with a history of quinidine-induced TdP?
Amiodarone can induce TdP in patients with a history of quinidine-induced TdP, and QT dispersion may serve as a potential marker.
Suggests potential cross-susceptibility to proarrhythmia between am.
We report a case of amiodarone induced torsades de pointes (TdP) associated with increase QT dispersion in a patient with a history of quinidine induced TdP. An increase in QT dispersion of > 100% was noted on the 12 lead surface ECG postamiodarone therapy. In summary, amiodarone has a potential to induce TdP in patients with a previous history of quinidine induced TdP. QT dispersion could be a potential marker of TdP in these patients.
No takes yet. Share an insight, caveat, or question.
Tran et al. (1997) conducted a case report in Torsades de pointes (n=1). Amiodarone was evaluated on Torsades de pointes and QT dispersion. Amiodarone induced torsades de pointes and an increase in QT dispersion of >100% in a patient with a history of quinidine-induced torsades de pointes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: