Key result
Acute myocardial infarction was associated with increased platelet aggregability peaking on days 14-16, while around 50% of patients showed decreased fibrinolytic activity at discharge.
Why the study?
How do platelet functions, coagulation, and fibrinolysis change over 3 weeks in uncomplicated acute myocardial infarction?
Population
12 patients with non-complicated acute transmural myocardial infarction
Design
Cohort
Follow-up
3 weeks
Authors
Loading...
May indicate prolonged post-MI thrombotic risk; leaves open whether targeting peak aggregability at 2 weeks improves outcomes.
Observational (n=12)
How do platelet functions, coagulation, and fibrinolysis change over 3 weeks in uncomplicated acute myocardial infarction?
In uncomplicated acute myocardial infarction, platelet aggregability initially decreases but peaks around 2 weeks, while fibrinolytic activity reaches its nadir at day 5.
Knudsen et al. (1979) conducted an observational in non-complicated acute transmural myocardial infarction (n=12). Acute myocardial infarction was associated with increased platelet aggregability peaking on days 14-16, while around 50% of patients showed decreased fibrinolytic activity at discharge.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: