Key result
Acute myocardial infarction was associated with significantly shorter whole blood clotting time within 24 hours and increased levels of fibrinogen and factors VIII, IX, and XI.
Why the study?
How do coagulation factors change following acute myocardial infarction compared to patients with similar symptoms but no infarction?
Population
20 patients presenting with symptoms of acute myocardial infarction
Comparison
Acute myocardial infarction vs Patients with similar symptoms but without…
Design
Cohort
Follow-up
10 days
Authors
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Suggests early hypercoagulability after AMI; leaves open whether factor-specific interventions improve outcomes.
Observational (n=20)
How do coagulation factors change following acute myocardial infarction compared to patients with similar symptoms but no infarction?
Acute myocardial infarction is associated with early shortening of whole blood clotting time and specific alterations in coagulation factors, indicating a hypercoagulable state.
Rennie et al. (2009) conducted an observational in Acute myocardial infarction (n=20). Acute myocardial infarction vs. Patients with similar symptoms but without myocardial infarction was evaluated on Changes in whole blood clotting time, plasma fibrinogen, and individual coagulation factors. Acute myocardial infarction was associated with significantly shorter whole blood clotting time within 24 hours and increased levels of fibrinogen and factors VIII, IX, and XI.
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