Key result
Low HDL-C (<30 mg/dL) was associated with a significantly increased risk of all stroke incidence compared to high HDL-C (≥60 mg/dL) (RR 2.89; 95% CI 1.35-6.20).
Why the study?
Does low HDL-C increase the risk of all stroke and ischemic stroke in Japanese men and women?
Cohort (n=4,989)
Does low HDL-C increase the risk of all stroke and ischemic stroke in Japanese men and women?
Effect estimate: RR 2.89 (95% CI 1.35 to 6.20)
Lower HDL-C levels are significantly and independently associated with an increased risk of all stroke and ischemic stroke in Japanese men and women.
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Low HDL-C may mark higher stroke risk in Japanese adults; hypothesis-generating, prospective trials needed before practice change.
Soyama et al. (2003) conducted a cohort in Stroke risk (n=4,989). Low HDL-C (<30 mg/dL) vs. High HDL-C (≥60 mg/dL) was evaluated on All stroke incidence (RR 2.89, 95% CI 1.35 to 6.20). Low HDL-C (<30 mg/dL) was associated with a significantly increased risk of all stroke incidence compared to high HDL-C (≥60 mg/dL) (RR 2.89; 95% CI 1.35-6.20).
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