Why the study?
While a positive association between non-HDL-C and CHD is established, associations between non-HDL-C and stroke subtypes have not been determined.
Does non-HDL-C level predict the risk of stroke subtypes and coronary heart disease in Japanese adults without prior CVD?
Does non-HDL-C level predict the risk of stroke subtypes and coronary heart disease in Japanese adults without prior CVD?
Lower non-HDL-C levels in Japanese men are associated with a decreased risk of large-artery occlusive infarction but an increased risk of intracerebral hemorrhage, highlighting a complex risk profile for lipid lowering.
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These associations should not yet change lipid management in Japanese men; hypothesis-generating for subtype-specific stroke risk models.
Saito et al. (2019) studied this question.
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