Key result
Animal models of heart failure lack a single perfect counterpart to human disease, requiring researchers to match specific models to the precise purpose of their study.
Population
Animal models of heart failure
Design
Review
Authors
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Supports purpose-specific animal model selection in heart failure research; leaves open pursuit of superior translational models.
This review highlights that while no perfect animal model of heart failure exists, models should be carefully selected based on the specific research question.
Arnolda et al. (1999) conducted a review in Heart failure. Animal models was evaluated. Animal models of heart failure lack a single perfect counterpart to human disease, requiring researchers to match specific models to the precise purpose of their study.
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