Key result
Animal HF models provide pathophysiological insights but fail to perfectly mimic the human syndrome.
Population
Animal models of heart failure (including dogs and rats)
Design
Review
Authors
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Animal models aid HF research but require human validation before clinical use; leaves open refinement of models that better mimic human disease.
This review highlights the utility and limitations of various animal models in studying heart failure pathophysiology and testing new therapies.
Eisner et al. (1995) conducted a review in Heart failure. Animal models was evaluated. Animal models of heart failure provide insights into pathophysiology and therapies, though no single model perfectly imitates the human syndrome.
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