Key result
Augmentation index derived from peripheral arterial tonometry was significantly higher in patients with coronary artery disease (P=0.008) and those with >5 cardiovascular risk factors (P=0.02).
Why the study?
Does Augmentation index derived from peripheral arterial tonometry correlate with cardiovascular risk factors and coronary artery disease?
Observational (n=186)
Does Augmentation index derived from peripheral arterial tonometry correlate with cardiovascular risk factors and coronary artery disease?
Effect estimate: AUC 0.604
p-value: p=<0.01
Augmentation index derived from peripheral arterial tonometry correlates with cardiovascular risk factors and the presence of coronary artery disease, suggesting utility in risk assessment.
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Higher augmentation index may associate with CAD and elevated risk burden; hypothesis-generating for risk stratification pending prospective studies.
Patvardhan et al. (2011) conducted an observational in Cardiovascular risk factors and coronary artery disease (n=186). Augmentation index (AIx) derived from peripheral arterial tonometry (PAT) vs. Patients with fewer risk factors or without coronary artery disease was evaluated on Association of AIx with cardiovascular risk factors and coronary artery disease (AUC 0.604, p=<0.01). Augmentation index derived from peripheral arterial tonometry was significantly higher in patients with coronary artery disease (P=0.008) and those with >5 cardiovascular risk factors (P=0.02).
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