Key result
A higher posterior wall thickness to cavity dimension ratio was associated with survival in childhood dilated cardiomyopathy or myocarditis (median 0.19 vs 0.13; P<0.005).
Why the study?
Does the ratio of end-diastolic posterior wall thickness to cavity dimensions predict survival or need for heart transplantation in children with dilated cardiomyopathy and myocarditis?
Population
16 children presenting with dilated cardiomyopathy/myocarditis
Design
Cohort
Follow-up
median 25 months
Authors
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Should not yet guide transplant timing in pediatric DCM/myocarditis; hypothesis-generating for wall-to-cavity ratio as prognostic marker.
Cohort (n=16)
Does the ratio of end-diastolic posterior wall thickness to cavity dimensions predict survival or need for heart transplantation in children with dilated cardiomyopathy and myocarditis?
p-value: p=< 0.005
A relatively thicker posterior wall (ratio > 0.17) is associated with better prognosis and recovery in childhood dilated cardiomyopathy and myocarditis, which may help guide timing for cardiac transplantation.
Carvalho et al. (1996) conducted a cohort in Childhood dilated cardiomyopathy and myocarditis (n=16). Posterior wall thickness to cavity dimension ratio was evaluated on Survival versus death or heart transplantation (p=< 0.005). A higher posterior wall thickness to cavity dimension ratio was associated with survival in childhood dilated cardiomyopathy or myocarditis (median 0.19 vs 0.13; P<0.005).
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