Key result
Pregnancy in pulmonary hypertension carries high risk, linked to a ~17% rate of cardiac complications.
Why the study?
Pulmonary hypertension is a life-threatening disease with significant maternal morbidity and mortality, warranting assessment of maternal and neonatal outcomes and associated risk factors.
What are the maternal and neonatal outcomes and risk factors for adverse events in pregnancies complicated by pulmonary hypertension?
Population
71 pregnancies in patients with PH who delivered at a tertiary care center in West China
Design
Retrospective analysis
Authors
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Supports multidisciplinary counseling for PH pregnancies; leaves open validation of risk predictors in prospective studies.
Cohort (n=71)
No
What are the maternal and neonatal outcomes and risk factors for adverse events in pregnancies complicated by pulmonary hypertension?
Pregnancy in women with pulmonary hypertension carries a high risk of maternal and fetal morbidity and mortality, with severe PH, right ventricular dysfunction, and NYHA class III/IV being key predictors of adverse events.
Liao et al. (2022) conducted a cohort in Pulmonary hypertension in pregnancy (n=71). Pregnancy with pulmonary hypertension was evaluated on Cardiac complications. Pregnancy in women with pulmonary hypertension carries high risks, with cardiac complications occurring in 16.9% of pregnancies (including 3 maternal deaths) and pregnancy complications in 28.2%.
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