Key result
High adiponectin levels increased the probability of the metabolically healthy obese phenotype in women (OR 3.02; 95% CI 1.95-4.67) and men (OR 2.14; 95% CI 1.1-4.06).
Why the study?
Are high plasma adiponectin levels associated with the metabolically healthy obese phenotype in adults?
Population
716 subjects (189 men, 527 women) aged 18-70 years, including obese (n=470, 65.6%) and nonobese subjects.
Comparison
High plasma adiponectin levels vs Lower plasma adiponectin levels
Design
Cross-sectional
Authors
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High adiponectin was associated with metabolically healthy obesity; extends murine data but remains hypothesis-generating.
Cross-Sectional (n=716)
Are high plasma adiponectin levels associated with the metabolically healthy obese phenotype in adults?
Effect estimate: OR 3.02 (women); OR 2.14 (men) (95% CI 1.95-4.67 (women); 1.1-4.06 (men))
p-value: p=<0.001 (women); 0.01 (men)
High plasma adiponectin levels are associated with a metabolically healthy obese phenotype, independent of age, insulin, and waist circumference.
Aguilar‐Salinas et al. (2008) conducted a cross-sectional in Obesity (n=716). High adiponectin concentrations vs. Low adiponectin concentrations was evaluated on Metabolically healthy obese phenotype (OR 3.02 (women); OR 2.14 (men), 95% CI 1.95-4.67 (women); 1.1-4.06 (men), p=<0.001 (women); 0.01 (men)). High adiponectin levels increased the probability of the metabolically healthy obese phenotype in women (OR 3.02; 95% CI 1.95-4.67) and men (OR 2.14; 95% CI 1.1-4.06).
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