Key result
Magnetic resonance imaging (MRI) accurately measured total adipose tissue volume in rats, correlating highly with computerized tomography (r=0.99, P<0.001) and chemical lipid extraction.
Why the study?
Does MRI accurately measure adipose tissue volume compared to CT and chemical analysis in rats?
Population
Rats (n=17) varying in weight (465-815 g) and percent body fat (5.4-31.1%)
Comparison
Magnetic resonance imaging for measuring adipose… vs X-ray computerized tomography and chemical…
Design
Preclinical
Authors
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MRI supports precise adipose volumetry in rat models; leaves open human translation and clinical validation.
Does MRI accurately measure adipose tissue volume compared to CT and chemical analysis in rats?
Effect estimate: r = 0.99
p-value: p=<0.001
MRI is a viable and accurate method for measuring visceral and subcutaneous adipose tissue volumes in rodents, comparable to CT and chemical analysis.
Ross et al. (1991) studied this question. Magnetic resonance imaging (MRI) vs. Computerized tomography (CT) and chemical analysis was evaluated on Correlation of total adipose tissue volumes between MRI and CT (r = 0.99, p=<0.001). Magnetic resonance imaging (MRI) accurately measured total adipose tissue volume in rats, correlating highly with computerized tomography (r=0.99, P<0.001) and chemical lipid extraction.
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