Key result
Prognostic factors including tumor grade (p=0.00005), histologic subtype (p=0.00025), tumor size ≥5 cm (p=0.005), surgical margins (p=0.0001), and invasion (p=0.008) predicted tumor mortality.
Why the study?
What are the prognostic factors for survival in patients with primary extremity liposarcoma undergoing surgical resection?
Cohort (n=83)
What are the prognostic factors for survival in patients with primary extremity liposarcoma undergoing surgical resection?
Tumor grade, histologic subtype, tumor size, surgical margins, and invasion of vital structures are significant prognostic factors for survival in primary extremity liposarcoma.
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These factors may refine postoperative risk stratification; leaves open prospective validation before guiding decisions.
Chang et al. (1990) conducted a cohort in Primary localized extremity liposarcoma (n=83). Surgical resection was evaluated on Tumor mortality. Prognostic factors including tumor grade (p=0.00005), histologic subtype (p=0.00025), tumor size ≥5 cm (p=0.005), surgical margins (p=0.0001), and invasion (p=0.008) predicted tumor mortality.