Population
Smooth-muscle alpha-actinin purified from chicken gizzard
Design
Preclinical
Authors
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Requires validation before clinical use in muscle disorders; extends molecular models of actin cross-linking.
The study clarifies the quaternary organization of smooth-muscle alpha-actinin, suggesting its effective actin-binding and cross-linking is based on the high flexibility of its terminal hooks.
Winkler et al. (1997) studied this question.
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