Key result
Routine postdilatation in STEMI primary PCI increases slow reflow odds ~11-fold vs no postdilatation.
Why the study?
Does routine postdilatation using non-compliant balloons improve coronary blood flow in STEMI patients undergoing PPCI without angiographic stent expansion problems?
Population
124 patients with ST segment elevation myocardial infarction undergoing primary percutaneous coronary…
Comparison
Routine postdilatation performed using… vs No postdilatation performed.
Design
RCT, Patients were randomized into two groups
Authors
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Avoid routine postdilatation in STEMI primary PCI without expansion issues; challenges assumptions favoring aggressive stent optimization.
RCT (n=124)
randomized
Does routine postdilatation using non-compliant balloons improve coronary blood flow in STEMI patients undergoing PPCI without angiographic stent expansion problems?
Effect estimate: OR 11.566 (95% CI 1.633 to 81.908)
Absolute Event Rate: 35.5% vs 14.5%
p-value: p=0.014
Routine postdilatation during primary PCI in STEMI patients without angiographic stent expansion problems is associated with an increased risk of slow reflow and should likely be avoided.
Soylu et al. (2018) conducted an RCT in ST segment elevation myocardial infarction (STEMI) (n=124). Routine postdilatation vs. No postdilatation was evaluated on Slow-reflow rate (OR 11.566, 95% CI 1.633 to 81.908, p=0.014). Routine postdilatation during primary PCI in STEMI patients without stent expansion problems significantly increased the risk of slow reflow compared to no postdilatation (35.5% vs 14.5%; OR 11.566).
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