Key result
Stent postdilation during primary percutaneous coronary intervention for STEMI was associated with a decreased risk of the device-oriented composite endpoint (HR 0.40; 95% CI 0.18-0.87; p=0.021).
Why the study?
Achieving optimal coronary stent apposition during PCI is not always feasible, and the risks and benefits of stent postdilation during PPCI for STEMI have remained controversial.
Does stent postdilation improve angiographic and clinical outcomes in patients with STEMI undergoing primary percutaneous coronary intervention?
Population
1,224 STEMI patients treated with PPCI
Comparison
Stent postdilation (n = 500) vs controls without postdilation (n = 724)
Design
Cohort study
Follow-up
348 ± 399 days
Authors
Loading...
Should not yet change postdilation practice in STEMI PCI; leaves open need for RCTs to confirm DOCE benefit.
Cohort (n=1,224)
Does stent postdilation improve angiographic and clinical outcomes in patients with STEMI undergoing primary percutaneous coronary intervention?
Effect estimate: HR 0.40 (95% CI 0.18-0.87)
Absolute Event Rate: 2.2% vs 5.8%
p-value: p=0.021
Selective stent postdilation during primary PCI for STEMI is associated with improved long-term device-oriented clinical outcomes without compromising immediate angiographic results.
Saadat et al. (2019) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=1,224). Stent postdilation vs. No stent postdilation was evaluated on Device-oriented composite endpoint (DOCE) (HR 0.40, 95% CI 0.18-0.87, p=0.021). Stent postdilation during primary percutaneous coronary intervention for STEMI was associated with a decreased risk of the device-oriented composite endpoint (HR 0.40; 95% CI 0.18-0.87; p=0.021).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: