Key result
Implementation of a liberal post-dilatation strategy during PCI significantly reduced 30-day major adverse cardiovascular events from 5.00% to 4.09% (OR 0.75).
Why the study?
Post-dilatation after PCI is used to optimize stent expansion and reduce complications, but its prognostic effects remain unclear and conflicting.
Does a liberal post-dilatation strategy improve 30-day MACE in patients undergoing percutaneous coronary intervention?
Population
10,153 patients undergoing PCI
Comparison
Post-implementation (2018-2020) vs pre-implementation (2015-2017) of a liberal post-dilatation strategy
Design
Pre-post-intervention cohort analysis
Follow-up
1 year
Authors
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Liberal post-dilatation during PCI may lower early MACE; hypothesis-generating and needs randomized confirmation before practice change.
Cohort (n=10,153)
No
Does a liberal post-dilatation strategy improve 30-day MACE in patients undergoing percutaneous coronary intervention?
Odds Ratio: 0.75 (95% CI 0.61–0.93)
Absolute Event Rate: 4.09% vs 5%
p-value: p=0.008
Implementing a liberal post-dilatation strategy during PCI is associated with significant reductions in 30-day MACE and 1-year mortality in a real-world cohort.
Slingerland et al. (2023) conducted a cohort in Patients undergoing percutaneous coronary intervention (PCI) (n=10,153). Liberal post-dilatation strategy vs. Standard post-dilatation strategy (pre-cohort) was evaluated on Major adverse cardiovascular events (MACE) at 30 days (OR 0.75, 95% CI 0.61-0.93, p=0.008). Implementation of a liberal post-dilatation strategy during PCI significantly reduced 30-day major adverse cardiovascular events from 5.00% to 4.09% (OR 0.75).
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