Key result
Residual pulmonary vascular obstruction severity at discharge in intermediate- to high-risk PE patients predicted a combined 6-month adverse outcome (OR 2.66; 95% CI 1.58-3.93).
Why the study?
Does residual pulmonary vascular obstruction at discharge predict adverse outcomes at 6 months in patients with intermediate- to high-risk pulmonary embolism?
Population
416 consecutive patients with intermediate- or high-risk pulmonary embolism who survived the acute phase…
Design
Cohort
Follow-up
6 months
Authors
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May support discharge risk stratification in intermediate- to high-risk PE; leaves open whether targeted interventions improve outcomes.
Cohort (n=416)
Does residual pulmonary vascular obstruction at discharge predict adverse outcomes at 6 months in patients with intermediate- to high-risk pulmonary embolism?
Effect estimate: OR 2.66 (95% CI 1.58-3.93)
Residual pulmonary vascular obstruction ≥35% at discharge is a strong predictor of 6-month mortality, recurrent PE, and heart failure in patients with intermediate- to high-risk pulmonary embolism.
Méneveau et al. (2012) conducted a cohort in Intermediate- or high-risk pulmonary embolism (n=416). Residual pulmonary vascular obstruction (RPVO) was evaluated on Combined endpoint at 6 months, including death, recurrent PE, and appearance of signs of heart failure (OR 2.66, 95% CI 1.58-3.93). Residual pulmonary vascular obstruction severity at discharge in intermediate- to high-risk PE patients predicted a combined 6-month adverse outcome (OR 2.66; 95% CI 1.58-3.93).
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